Sugi Predict

Sugi Predict / Compounds / SCHEMBL25818448

SCHEMBL25818448

SCHEMBL25818448

Clc1nc(-c2cccc(-c3ccc4ccc(-c5ccccc5)cc4c3)c2)nc(-c2ccc3c(c2)sc2cc(-c4ccccc4)ccc23)n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 2/20 0.39
▸ ESR2 Q92731 2/20 0.39
▸ LIMK1 P53667 3/20 0.38
▸ PIK3CA P42336 1/20 0.38
▸ PI4KA P42356 1/20 0.38
▸ PI4KB Q9UBF8 1/20 0.38
▸ F9 P00740 2/20 0.35
▸ MEN1 O00255 2/20 0.35
▸ ALDH1A1 P00352 2/20 0.35
▸ HPGD P15428 2/20 0.35
▸ KMT2A Q03164 2/20 0.35
▸ L3MBTL1 Q9Y468 2/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ MCL1 Q07820 1/20 0.34
▸ BACE1 P56817 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ GP6 Q9HCN6 1/20 0.33
▸ LIMK2 P53671 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25818423 0.96 ALDH1A1 (0.36) ESR1ESR2LIMK1PIK3CAPI4KA
SCHEMBL25818432 0.92 ALDH1A1 (0.37) ESR1ESR2LIMK1PIK3CAPI4KA
SCHEMBL25818453 0.91 ALDH1A1 (0.36) ESR1ESR2LIMK1MEN1ALDH1A1
SCHEMBL25706239 0.91 ALDH1A1 (0.40) LIMK1PIK3CAPI4KAPI4KBMEN1
SCHEMBL24659050 0.90 PIK3CA (0.42) LIMK1PIK3CAPI4KAPI4KBF9
SCHEMBL25818535 0.90 LIMK1 (0.33) ESR1ESR2LIMK1PIK3CAPI4KA
SCHEMBL22161420 0.90 ALDH1A1 (0.39) LIMK1PIK3CAPI4KAPI4KBMEN1
SCHEMBL25818528 0.89 PIM3 (0.38) ESR1ESR2LIMK1PIK3CAPI4KA
SCHEMBL25818561 0.89 LIMK1 (0.33) ESR1ESR2LIMK1PIK3CAPI4KA
SCHEMBL23437788 0.88 ALDH1A1 (0.40) LIMK1PIK3CAPI4KAPI4KBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917914-B1 Compound for organic electronic element, organic electronic element using the same, and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2024-02-27 — — US disclosed
US-20230225206-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2023-07-13 — — US disclosed
US-20230225206-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2023-07-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11917914-B1 Compound for organic electronic element, organic electronic element using the same, and an electronic device thereof NFE2L2, ESR1, OR51E2 ESR1 2/4885ESR2 14/4885LIMK1 905/4885
US-20230225206-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF NFE2L2, ESR1, OR51E2 ESR1 2/4885ESR2 14/4885LIMK1 905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.