SCHEMBL25818580

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL26668602	0.86	KMT2A (0.41)	ALDH1A1KMT2AMEN1HCAR3GRIN2D
	SCHEMBL26668820	0.83	KMT2A (0.40)	ALDH1A1KMT2AMEN1HCAR3GRIN2D
	SCHEMBL14764443	0.82	ALDH1A1 (0.50)	ALDH1A1KMT2AMEN1HCAR3MAPT
	SCHEMBL15228630	0.82	ALDH1A1 (0.50)	ALDH1A1KMT2AMEN1HCAR3MAPT
	SCHEMBL22032212	0.81	KMT2A (0.50)	ALDH1A1KMT2AMEN1HCAR3GRIN2D
	SCHEMBL16750263	0.76	MEN1 (0.43)	ALDH1A1KMT2AMEN1HCAR3GRIN2D
	SCHEMBL29558653	0.76	MEN1 (0.43)	ALDH1A1KMT2AMEN1HCAR3GRIN2D
	SCHEMBL10974753	0.74	ALDH1A1 (0.54)	ALDH1A1KMT2AMEN1HCAR3MAPT
	SCHEMBL31533512	0.74	MEN1 (0.44)	ALDH1A1KMT2AMEN1GRIN2DGRIN3B
	SCHEMBL1653800	0.74	ALDH1A1 (0.54)	ALDH1A1KMT2AMEN1HCAR3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.