Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 5/20 | 0.32 |
| ▸ | DRD4 | P21917 | 5/20 | 0.32 |
| ▸ | DRD3 | P35462 | 5/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25818877 | 0.86 | DRD2 (0.32) | DRD2DRD4DRD3GRM5 | |
| SCHEMBL25104686 | 0.85 | PIK3R1 (0.35) | DRD2DRD4DRD3GRM5 | |
| SCHEMBL22307364 | 0.84 | — | — | |
| SCHEMBL22235206 | 0.81 | RXFP1 (0.36) | — | |
| SCHEMBL31600410 | 0.81 | NOS3 (0.33) | NOS3NOS2 | |
| Hydrochloric Acid SCHEMBL31600038 | 0.80 | NOS3 (0.33) | NOS3NOS2 | |
| SCHEMBL24163731 | 0.78 | GRM5 (0.42) | GRM5 | |
| SCHEMBL22101725 | 0.74 | GRIN1 (0.40) | NOS3NOS2 | |
| SCHEMBL20822280 | 0.72 | SMN1; SMN2 (0.31) | GRM5 | |
| SCHEMBL29966264 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133217-A1 | 2-(INDAZOL-5-YL)-6-(PIPERIDIN-4-YL)-1,7-NAPHTHYRIDINE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS FOR SPLICING NUCLEIC ACIDS AND FOR THE TREATMENT OF PROLIFERATIVE DISEASES | REMIX THERAPEUTICS INC. (US) | 2023-07-13 | — | — | WO | disclosed |