Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25104683 | 0.86 | ATP4A (0.34) | — | |
| SCHEMBL25105540 | 0.81 | HTT (0.33) | — | |
| SCHEMBL20356284 | 0.80 | EGFR (0.38) | — | |
| SCHEMBL25527558 | 0.80 | — | — | |
| SCHEMBL25105584 | 0.78 | EGFR (0.31) | — | |
| SCHEMBL25253714 | 0.77 | — | — | |
| SCHEMBL25539251 | 0.71 | AKT1 (0.34) | PDE10A | |
| SCHEMBL22101522 | 0.70 | PIK3CB (0.37) | — | |
| SCHEMBL22101725 | 0.70 | GRIN1 (0.40) | KDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL22101540 | 0.70 | CYP2C9 (0.35) | PDE10AKDM4EALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133217-A1 | 2-(INDAZOL-5-YL)-6-(PIPERIDIN-4-YL)-1,7-NAPHTHYRIDINE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS FOR SPLICING NUCLEIC ACIDS AND FOR THE TREATMENT OF PROLIFERATIVE DISEASES | REMIX THERAPEUTICS INC. (US) | 2023-07-13 | — | — | WO | disclosed |