Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 17/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 12/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22101697 | 0.82 | KCNQ3 (0.34) | PIK3CBKCNQ3KCNQ2RAD51 | |
| SCHEMBL22101454 | 0.82 | KCNQ3 (0.35) | KCNQ3KCNQ2RAD51 | |
| SCHEMBL22101486 | 0.82 | KCNQ3 (0.35) | KCNQ3KCNQ2RAD51 | |
| SCHEMBL22393588 | 0.81 | KCNQ3 (0.36) | KCNQ3KCNQ2RAD51 | |
| SCHEMBL22101540 | 0.76 | CYP2C9 (0.35) | PIK3CBPIK3CDPIK3CA | |
| SCHEMBL22101725 | 0.76 | GRIN1 (0.40) | TDP1L3MBTL1 | |
| SCHEMBL22101865 | 0.73 | KCNQ3 (0.31) | PIK3CBKCNQ3KCNQ2RAD51 | |
| SCHEMBL22101541 | 0.72 | MAPT (0.35) | PIK3CB | |
| SCHEMBL22101539 | 0.70 | FFAR4 (0.35) | PIK3CB | |
| SCHEMBL25818875 | 0.70 | PDE10A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666772-A1 | DIARYLTHIOHYDANTOIN COMPOUND AS ANDROGEN RECEPTOR ANTAGONIST | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-06-17 | — | — | EP | disclosed |