SCHEMBL258189

SCHEMBL258189

C=Cc1cc(C=C)c2ccccc2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
TSHR P16473 2/20 0.41
HSD17B10 Q99714 2/20 0.38
HIF1A Q16665 1/20 0.38
CYP1B1 Q16678 1/20 0.38
ESR1 P03372 2/20 0.35
ESR2 Q92731 2/20 0.35
TRPM4 Q8TD43 1/20 0.34
PTGS1 P23219 1/20 0.34
PTGS2 P35354 1/20 0.34
SIRT2 Q8IXJ6 1/20 0.34
SIRT1 Q96EB6 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
CYP2A6 P11509 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
HTR2A P28223 1/20 0.33
NQO2 P16083 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29434181 1.00 ALDH1A1 (0.41) ALDH1A1TSHRHSD17B10HIF1ACYP1B1
SCHEMBL31047608 0.79 ESR1 (0.41) ALDH1A1TSHRESR1ESR2TDP1
SCHEMBL17628516 0.79 ESR1 (0.41) ALDH1A1TSHRESR1ESR2TDP1
SCHEMBL31180384 0.78 TRPM4 (0.46) ALDH1A1TSHRHSD17B10HIF1ACYP1B1
SCHEMBL1813416 0.78 TRPM4 (0.46) ALDH1A1TSHRHSD17B10HIF1ACYP1B1
SCHEMBL1506780 0.78 NQO2 (0.55) ALDH1A1HSD17B10HIF1ACYP1B1ESR1
SCHEMBL21045089 0.78 CYP1A2 (0.55) ALDH1A1HSD17B10HIF1ACYP1B1ESR1
SCHEMBL2046730 0.78 CYP2A6 (0.40) ALDH1A1TSHRHSD17B10HIF1ACYP1B1
SCHEMBL29592963 0.78 TP53 (0.41) ALDH1A1TSHRPTGS1PTGS2SIRT2
SCHEMBL12986970 0.78 TP53 (0.41) ALDH1A1TSHRPTGS1PTGS2SIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 520 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3239187-B1 PROCESS FOR PRODUCING AROMATIC VINYL/CONJUGATED DIENE COPOLYMER AND PRODUCT OF HYDROGENATION THEREOF KURARAY CO (JP) 2024-09-04 EP claimed
US-10978736-B2 Composite membrane for secondary battery, method of preparing the same, and secondary battery including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-04-13 US claimed
CN-107207655-B The modified polymer based on conjugated diene, preparation method and the rubber composition comprising it LG化学株式会社 2019-11-08 CN claimed
CN-110391396-A For the composite membrane of secondary cell, preparation method and including its secondary cell 三星电子株式会社 2019-10-29 CN claimed
US-20190326631-A1 COMPOSITE MEMBRANE FOR SECONDARY BATTERY, METHOD OF PREPARING THE SAME, AND SECONDARY BATTERY INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-10-24 US claimed
US-10414841-B2 Modified conjugated diene-based polymer, method for preparing the same and rubber composition including the same LG CHEM, LTD. (KR) 2019-09-17 US claimed
US-20180016369-A1 MODIFIED CONJUGATED DIENE-BASED POLYMER, METHOD FOR PREPARING THE SAME AND RUBBER COMPOSITION INCLUDING THE SAME LG CHEM, LTD. (KR) 2018-01-18 US claimed
EP-3246344-A1 MODIFIED CONJUGATED DIENE-BASED POLYMER, METHOD FOR PREPARING SAME, AND RUBBER COMPOSITION CONTAINING SAME LG Chem, Ltd. (KR) 2017-11-22 EP claimed
CN-107207655-A The modified polymer based on conjugated diene, its preparation method and the rubber composition comprising it LG化学株式会社 2017-09-26 CN claimed
CN-105470569-A Electrolyte, method of preparing electrolyte, and secondary battery including electrolyte SAMSUNG ELECTRONICS CO LTD 2016-04-06 CN claimed
US-5780551-A UNSYMMETRICALLY PROTECTED; FROM ONE OR MORE CONJUGATED DIENE OR ALKENYLAROMATIC COMPOUND FMC CORPORATION (US) 1998-07-14 US claimed
WO-1997016465-A1 TELECHELIC POLYMERS FROM MIXED INITIATOR FMC CORPORATION (US) 1997-05-09 WO claimed
EP-0573893-B1 Butadiene copolymer SUMITOMO CHEMICAL CO (JP) 1997-01-22 EP claimed
WO-1995016727-A1 MULTI-ARM CATIONIC STAR POLYMERS THE UNIVERSITY OF AKRON (US) 1995-06-22 WO claimed
US-5395885-A For example, isobutylene-divinylbenzene THE UNIVERSITY OF AKRON (US) 1995-03-07 US claimed
US-5290878-A Butadiene copolymer and process for preparing same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-03-01 US claimed
EP-0573893-A2 Butadiene copolymer SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1993-12-15 EP claimed
EP-0046668-B1 PROCESS FOR PRODUCING HIGH IMPACT POLYSTYRENE JAPAN ELASTOMER COMPANY LIMITED (JP) 1985-11-13 EP claimed
US-4482677-A POLYENE, ORGANOLITIUM INITIATOR, STAR POLYMERS JAPAN ELASTOMER CO., LTD. (JP) 1984-11-13 US claimed
EP-0046668-A2 Process for producing high impact polystyrene JAPAN ELASTOMER COMPANY LIMITED (JP) 1982-03-03 EP claimed