Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22946630 | 0.85 | ALDH1A1 (0.47) | KDM4EMAPTALDH1A1NSD2NQO2 | |
| SCHEMBL25600581 | 0.81 | MAPT (0.50) | KDM4EMAPTALDH1A1NSD2NOTUM | |
| SCHEMBL24163749 | 0.81 | MAPT (0.43) | KDM4EMAPTALDH1A1NSD2NQO2 | |
| SCHEMBL16432372 | 0.79 | AXL (0.42) | KDM4EMAPTALDH1A1NSD2NQO2 | |
| SCHEMBL24033484 | 0.79 | ALDH1A1 (0.50) | KDM4EMAPTALDH1A1NSD2NQO2 | |
| Hydrochloric Acid SCHEMBL31600805 | 0.78 | ALDH1A1 (0.49) | KDM4EMAPTALDH1A1NSD2NQO2 | |
| SCHEMBL29318293 | 0.77 | MAPT (0.40) | KDM4EMAPTALDH1A1NSD2NQO2 | |
| SCHEMBL29003789 | 0.77 | KDM4E (0.40) | KDM4EMAPTALDH1A1NSD2NQO2 | |
| SCHEMBL23643801 | 0.76 | ALDH1A1 (0.42) | KDM4EMAPTALDH1A1NSD2NQO2 | |
| SCHEMBL29109591 | 0.76 | PGK1 (0.44) | KDM4EMAPTALDH1A1NSD2NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133217-A1 | 2-(INDAZOL-5-YL)-6-(PIPERIDIN-4-YL)-1,7-NAPHTHYRIDINE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS FOR SPLICING NUCLEIC ACIDS AND FOR THE TREATMENT OF PROLIFERATIVE DISEASES | REMIX THERAPEUTICS INC. (US) | 2023-07-13 | — | — | WO | disclosed |