Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 9/20 | 0.70 |
| ▸ | THRA | P10827 | 8/20 | 0.70 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.70 |
| ▸ | ITGAV | P06756 | 6/20 | 0.70 |
| ▸ | PPARG | P37231 | 5/20 | 0.70 |
| ▸ | RXRA | P19793 | 3/20 | 0.70 |
| ▸ | PCNA | P12004 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | PGR | P06401 | 2/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | HTR2B | P41595 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25819195 | 0.96 | THRB (0.65) | THRBTHRAITGB3ITGAVPPARG | |
| SCHEMBL25955807 | 0.93 | THRB (0.68) | THRBTHRAITGB3ITGAVPPARG | |
| SCHEMBL25819213 | 0.89 | THRB (0.70) | THRBTHRAITGB3ITGAVPPARG | |
| SCHEMBL19679633 | 0.88 | THRB (0.61) | THRBTHRAITGB3ITGAVPPARG | |
| SCHEMBL19679634 | 0.87 | THRB (0.60) | THRBTHRAITGB3ITGAVPPARG | |
| SCHEMBL6858155 | 0.86 | THRB (0.70) | THRBTHRAITGB3ITGAVPPARG | |
| SCHEMBL16155956 | 0.85 | THRB (0.68) | THRBTHRAITGB3ITGAVPPARG | |
| SCHEMBL12764501 | 0.85 | THRB (0.68) | THRBTHRAITGB3ITGAVPPARG | |
| SCHEMBL12764500 | 0.85 | THRB (0.68) | THRBTHRAITGB3ITGAVPPARG | |
| SCHEMBL19696744 | 0.85 | THRB (0.76) | THRBTHRAITGB3ITGAVPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11723888-B2 | Polymer conjugated thyrointegrin antagonists | NANOPHARMACEUTICALS LLC (US) | 2023-08-15 | — | — | US | disclosed |
| US-11723888-B2 | Polymer conjugated thyrointegrin antagonists | NANOPHARMACEUTICALS LLC (US) | 2023-08-15 | — | — | US | disclosed |
| US-20230181501-A1 | POLYMER CONJUGATED THYROINTEGRIN ANTAGONISTS | NANOPHARMACEUTICALS LLC | 2023-06-15 | — | — | US | disclosed |
| US-20230181501-A1 | POLYMER CONJUGATED THYROINTEGRIN ANTAGONISTS | NANOPHARMACEUTICALS LLC | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11723888-B2 | Polymer conjugated thyrointegrin antagonists | TEK, HDGF, PTGFR | THRB 16/4885THRA 12/4885ITGB3 284/4885 |
| US-20230181501-A1 | POLYMER CONJUGATED THYROINTEGRIN ANTAGONISTS | TEK, HDGF, PTGFR | THRB 16/4885THRA 12/4885ITGB3 284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.