Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 15/20 | 0.51 |
| ▸ | GSK3B | P49841 | 11/20 | 0.51 |
| ▸ | SRC | P12931 | 7/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 7/20 | 0.50 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.50 |
| ▸ | GSK3A | P49840 | 1/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | ULK1 | O75385 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31471763 | 0.84 | AURKA (0.50) | AURKAGSK3BSRCAURKBEIF2AK2 | |
| SCHEMBL785406 | 0.84 | AURKA (0.70) | AURKAGSK3BSRCAURKBEIF2AK2 | |
| SCHEMBL30147253 | 0.84 | AURKA (0.70) | AURKAGSK3BSRCAURKBEIF2AK2 | |
| SCHEMBL4073913 | 0.81 | SPAST (0.58) | AURKAGSK3BSRCAURKBEIF2AK2 | |
| SCHEMBL31471743 | 0.81 | AURKA (0.50) | AURKAGSK3BSRCAURKBEIF2AK2 | |
| SCHEMBL786513 | 0.80 | ULK1 (0.65) | GSK3BSRCAURKBNTRK1ULK1 | |
| SCHEMBL29618398 | 0.80 | ULK1 (0.65) | GSK3BSRCAURKBNTRK1ULK1 | |
| SCHEMBL31471762 | 0.76 | APP (0.52) | AURKAGSK3BSRCAURKBEIF2AK2 | |
| SCHEMBL2206599 | 0.74 | APP (0.50) | AURKAGSK3BSRCAURKBEIF2AK2 | |
| SCHEMBL786130 | 0.73 | APP (0.56) | AURKAPDE5AAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023123883-A1 | METHOD FOR PREPARING QUINAZOLINE DERIVATIVE AND ANALOG THEREOF AND USE THEREOF | 沈阳药科大学 | 2023-07-06 | — | — | WO | disclosed |