SCHEMBL25819427

SCHEMBL25819427

PN1CCCc2c(Br)cccc2C1

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 3/20 0.48
ABHD6 Q9BV23 6/20 0.42
AKR1C3 P42330 1/20 0.41
PRMT6 Q96LA8 1/20 0.41
PRMT1 Q99873 1/20 0.41
ACACB O00763 3/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TRAP1 Q12931 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10455390 0.74 TSHR (0.50) CARM1MEN1KMT2A
SCHEMBL29428684 0.73 BCL2L1 (0.56) CARM1MEN1KMT2A
SCHEMBL1513686 0.73 BCL2L1 (0.50) CARM1ABHD6MEN1KMT2A
SCHEMBL29459963 0.73 BCL2L1 (0.50) CARM1ABHD6MEN1KMT2A
SCHEMBL1513618 0.73 BCL2L1 (0.56) CARM1MEN1KMT2A
SCHEMBL16076617 0.71 MAOA (0.57) CARM1ABHD6AKR1C3PRMT6PRMT1
SCHEMBL13464088 0.71 ABHD6 (0.47) CARM1ABHD6AKR1C3PRMT6PRMT1
SCHEMBL19643944 0.71 CARM1 (0.42) CARM1ABHD6AKR1C3PRMT6PRMT1
SCHEMBL3976079 0.68
SCHEMBL4006320 0.68 ABHD6 (0.47) CARM1ABHD6AKR1C3PRMT6PRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230219923-A1 KINASE INHIBITORS VIDYA THERAPEUTICS, INC. 2023-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219923-A1 KINASE INHIBITORS BTK, ABL1, LYN CARM1 1821/4885ABHD6 3093/4885AKR1C3 4341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.