Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 7/20 | 0.39 |
| ▸ | CDK2 | P24941 | 6/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | PRKACG | P22612 | 1/20 | 0.33 |
| ▸ | PRKACB | P22694 | 1/20 | 0.33 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18521155 | 0.89 | CDK1 (0.41) | CDK1CDK2CCNB1CCNE1HSP90AB1 | |
| SCHEMBL18521594 | 0.86 | CDK1 (0.44) | CDK1CDK2CCNB1CCNE1HSP90AB1 | |
| SCHEMBL24239210 | 0.79 | CDK1 (0.53) | CDK1CDK2CCNB1CCNE1HSP90AB1 | |
| SCHEMBL18521819 | 0.78 | CDK1 (0.44) | CDK1CDK2CCNB1CCNE1HSP90AB1 | |
| SCHEMBL12522765 | 0.78 | CDK1 (0.50) | CDK1CDK2CCNB1CCNE1HSP90AB1 | |
| SCHEMBL18521191 | 0.77 | CCNE1 (0.67) | CDK1CDK2CCNB1CCNE1HSP90AB1 | |
| SCHEMBL22571190 | 0.74 | PI4KA (0.45) | CDK1CDK2CCNB1CCNE1HSP90AB1 | |
| SCHEMBL22474871 | 0.74 | CCNE1 (0.51) | CDK1CDK2CCNB1CCNE1HSP90AB1 | |
| SCHEMBL20782336 | 0.74 | CDK1 (0.58) | CDK1CDK2CCNB1CCNE1HSP90AB1 | |
| SCHEMBL12451379 | 0.74 | CDK1 (0.63) | CDK1CDK2CCNB1CCNE1PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685761-B2 | Cyclic di-nucleotide compounds as sting agonists | MERCK SHARP & DOHME LLC (US) | 2023-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11685761-B2 | Cyclic di-nucleotide compounds as sting agonists | STING1, CGAS, IFNAR1 | CDK1 1548/4885CDK2 3886/4885CCNB1 2850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.