SCHEMBL25819841

SCHEMBL25819841

CC#Cc1cc(F)c(C=O)c(F)c1Br

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25819843 0.80
SCHEMBL17942556 0.74 CA12 (0.32) CYP3A4CYP2C9CYP2C19
SCHEMBL4719503 0.74 ERN1 (0.36)
SCHEMBL13179007 0.71 ERN1 (0.30)
SCHEMBL25819840 0.67 ESR1 (0.30)
SCHEMBL4720705 0.67 ERN1 (0.36) CYP3A4CYP2C9CYP2C19
SCHEMBL25259877 0.66 CA1 (0.37)
SCHEMBL1591447 0.66 PRKDC (0.32) CYP3A4CYP2C9CYP2C19
SCHEMBL30849780 0.66 ERN1 (0.33) CYP3A4CYP2C9CYP2C19
SCHEMBL29979088 0.66 PRKDC (0.33) CYP3A4CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023125182-A1 PROPIONIC ACID DERIVATIVE AND MEDICAL USE THEREOF 海思科医药集团股份有限公司 2023-07-06 WO disclosed