SCHEMBL25819840

SCHEMBL25819840

CC#Cc1cc(F)cc(F)c1Br

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2651893 0.74 TRPV4 (0.39) ESR1ESR2
SCHEMBL919665 0.71 KDM1A (0.42)
SCHEMBL4719503 0.71 ERN1 (0.36)
SCHEMBL6553272 0.69 KDM1A (0.41)
SCHEMBL25819841 0.67 CYP3A4 (0.31)
SCHEMBL8309828 0.66 RAPGEF4 (0.40)
SCHEMBL15490066 0.66 ESR1 (0.34) ESR1ESR2
SCHEMBL3838838 0.64 MAPT (0.39)
SCHEMBL29364024 0.64 MAPT (0.39)
SCHEMBL1981891 0.64 GRM5 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023125182-A1 PROPIONIC ACID DERIVATIVE AND MEDICAL USE THEREOF 海思科医药集团股份有限公司 2023-07-06 WO disclosed