Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 6/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | DHFR | P00374 | 6/20 | 0.49 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25821806 | 0.89 | KDM4E (0.56) | CYP2D6KCNH2KDM4EALDH1A1 | |
| SCHEMBL25821832 | 0.87 | CYP2D6 (0.57) | CYP2D6KCNH2TSHRCNR1CNR2 | |
| SCHEMBL4568871 | 0.86 | PPARA (0.61) | CYP2D6KCNH2TSHRCNR1CNR2 | |
| SCHEMBL17509810 | 0.85 | PPARA (0.68) | CYP2D6KCNH2TSHRCNR1CNR2 | |
| SCHEMBL17509804 | 0.85 | PPARA (0.68) | CYP2D6KCNH2TSHRCNR1CNR2 | |
| SCHEMBL17509791 | 0.85 | PPARA (0.68) | CYP2D6KCNH2TSHRCNR1CNR2 | |
| SCHEMBL17509796 | 0.85 | PPARA (0.68) | CYP2D6KCNH2TSHRCNR1CNR2 | |
| SCHEMBL17509797 | 0.85 | PPARA (0.68) | CYP2D6KCNH2TSHRCNR1CNR2 | |
| SCHEMBL17509789 | 0.85 | PPARA (0.68) | CYP2D6KCNH2TSHRCNR1CNR2 | |
| SCHEMBL17509795 | 0.85 | PPARA (0.68) | CYP2D6KCNH2TSHRCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | CYP2D6 3632/4885KCNH2 4102/4885TSHR 2971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.