Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | IP6K1 | Q92551 | 6/20 | 0.42 |
| ▸ | IP6K3 | Q96PC2 | 6/20 | 0.42 |
| ▸ | IP6K2 | Q9UHH9 | 6/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25820139 | 0.89 | SLC2A1 (0.47) | TRPV1CCNCCDK8NPC1RAB9A | |
| SCHEMBL25820137 | 0.87 | HRH4 (0.48) | TRPV1DPP4CCNCCDK8IP6K1 | |
| SCHEMBL25820141 | 0.86 | TRPV1 (0.43) | TRPV1DPP4CCNCCDK8IP6K1 | |
| SCHEMBL23809376 | 0.78 | ACE2 (0.55) | IP6K1IP6K3IP6K2ACE2NPC1 | |
| SCHEMBL25820095 | 0.77 | HTR1A (0.51) | TRPV1KDM4EPOLBALDH1A1LMNA | |
| SCHEMBL25820094 | 0.77 | SLC22A12 (0.42) | TRPV1MTNR1AMTNR1B | |
| SCHEMBL25820130 | 0.76 | KDM4E (0.43) | TRPV1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL25820075 | 0.76 | CCNC (0.42) | TRPV1CCNCCDK8 | |
| SCHEMBL25820089 | 0.75 | PIK3CA (0.51) | — | |
| SCHEMBL4641324 | 0.75 | TDP1 (0.50) | IP6K1IP6K3IP6K2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | TRPV1 4750/4885DPP4 3843/4885CCNC 821/4885 |
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | TRPV1 4682/4885DPP4 3650/4885CCNC 491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.