Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | CBFB | Q13951 | 1/20 | 0.34 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10045001 | 0.84 | SLC22A12 (0.48) | SLC22A12CYP19A1RECQLPLAUMAOA | |
| SCHEMBL25820095 | 0.80 | HTR1A (0.51) | SLC22A12CYP19A1TRPV1ROCK2IRAK4 | |
| SCHEMBL25820130 | 0.78 | KDM4E (0.43) | SLC22A12TRPV1ROCK2MTNR1AMTNR1B | |
| SCHEMBL25820075 | 0.78 | CCNC (0.42) | TRPV1ROCK2 | |
| SCHEMBL26030647 | 0.78 | SLC22A12 (0.44) | SLC22A12CYP19A1GABRA1RECQLPLAU | |
| SCHEMBL26664503 | 0.78 | GABRA1 (0.47) | GABRA1GABRB2LOXL2 | |
| SCHEMBL25820141 | 0.77 | TRPV1 (0.43) | CYP19A1TRPV1ROCK2MTNR1AMTNR1B | |
| SCHEMBL25820138 | 0.77 | TRPV1 (0.45) | TRPV1MTNR1AMTNR1B | |
| SCHEMBL25820139 | 0.77 | SLC2A1 (0.47) | TRPV1MTNR1AMTNR1B | |
| SCHEMBL25820108 | 0.76 | IP6K1 (0.43) | TRPV1ROCK2LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | SLC22A12 3664/4885CYP19A1 731/4885GABRA1 3307/4885 |
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | SLC22A12 3810/4885CYP19A1 602/4885GABRA1 3364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.