Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | FADS1 | O60427 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2091354 | 0.87 | FADS1 (0.56) | HPGDALOX15FADS1MEN1KMT2A | |
| SCHEMBL14986223 | 0.85 | HPGD (0.61) | HPGDALOX15FADS1KDM4EMEN1 | |
| SCHEMBL2091351 | 0.84 | FADS1 (0.54) | HPGDALOX15FADS1KDM4EMEN1 | |
| SCHEMBL12067305 | 0.83 | HPGD (0.58) | HPGDALOX15FADS1KDM4EMEN1 | |
| SCHEMBL14983611 | 0.83 | HPGD (0.58) | HPGDALOX15FADS1KDM4EMEN1 | |
| SCHEMBL10192111 | 0.82 | ALOX15 (0.69) | HPGDALOX15KDM4EMEN1KMT2A | |
| SCHEMBL10749929 | 0.82 | HPGD (0.69) | HPGDALOX15KDM4EMEN1KMT2A | |
| SCHEMBL31331879 | 0.82 | HPGD (0.69) | HPGDALOX15KDM4EMEN1KMT2A | |
| SCHEMBL12743181 | 0.81 | FADS1 (0.51) | HPGDALOX15FADS1MEN1KMT2A | |
| SCHEMBL21349101 | 0.81 | MAPK1 (0.62) | HPGDALOX15FADS1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
| US-9133225-B2 | Dual targeting anticancer agents | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-09-15 | — | — | US | disclosed |
| US-20140274988-A1 | DUAL TARGETING ANTICANCER AGENTS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | HPGD 2768/4885ALOX15 3097/4885FADS1 2478/4885 |
| US-20140274988-A1 | DUAL TARGETING ANTICANCER AGENTS | CCNE1, CCNE2, VHL | HPGD 304/4885ALOX15 1230/4885FADS1 3355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.