Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 12/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29977115 | 0.86 | TDP1 (0.36) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL25814978 | 0.86 | TDP1 (0.36) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL25825000 | 0.84 | TDP1 (0.37) | ALDH1A1KDM4EMAPTHSD17B10MEN1 | |
| SCHEMBL26967275 | 0.82 | TP53 (0.34) | MAPTMEN1KMT2ATDP1 | |
| SCHEMBL25820500 | 0.81 | KDM4E (0.47) | ALDH1A1KDM4EMAPTHSD17B10MEN1 | |
| SCHEMBL24616284 | 0.76 | SOS1 (0.36) | ALDH1A1KDM4EMAPTHSD17B10MEN1 | |
| SCHEMBL29071023 | 0.75 | TP53 (0.33) | ALDH1A1KDM4EMAPTHSD17B10MEN1 | |
| SCHEMBL25994930 | 0.74 | TP53 (0.35) | ALDH1A1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL25820439 | 0.74 | KDM4E (0.55) | ALDH1A1KDM4EMAPTHSD17B10MEN1 | |
| SCHEMBL29810959 | 0.74 | SOS1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125989-A1 | QUINAZOLINE COMPOUND AND APPLICATION THEREOF | 上海医药集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |