Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31048944 | 0.87 | GAA (0.44) | KDM4EALDH1A1MAPTKMT2ARXFP1 | |
| SCHEMBL25824998 | 0.83 | CA12 (0.41) | KDM4EALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL25815028 | 0.83 | CA12 (0.41) | KDM4EALDH1A1MAPTL3MBTL1TDP1 | |
| SCHEMBL25820439 | 0.82 | KDM4E (0.55) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL25820378 | 0.81 | ALDH1A1 (0.40) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL1567678 | 0.69 | KDM4E (0.52) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL21318015 | 0.69 | KDM4E (0.58) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL5863618 | 0.69 | KDM4E (0.51) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL1654418 | 0.69 | KDM4E (0.51) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL17111962 | 0.69 | TSHR (0.54) | KDM4EALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125989-A1 | QUINAZOLINE COMPOUND AND APPLICATION THEREOF | 上海医药集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |