SCHEMBL25825000 — predicted protein targets

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	TDP1	Q9NUW8	3/20	0.37

▸	NPSR1	Q6W5P4	2/20	0.37

▸	TP53	P04637	1/20	0.37

▸	HTT	P42858	1/20	0.37

▸	POLB	P06746	2/20	0.34

▸	SMN1; SMN2	Q16637	1/20	0.34

▸	KDM4E	B2RXH2	2/20	0.34

▸	LMNA	P02545	1/20	0.34

▸	KMT2A	Q03164	3/20	0.33

▸	MAPT	P10636	3/20	0.33

▸	MEN1	O00255	2/20	0.33

▸	TSHR	P16473	2/20	0.33

▸	HSD17B10	Q99714	1/20	0.33

▸	CA12	O43570	2/20	0.33

▸	CA1	P00915	2/20	0.33

▸	CA2	P00918	2/20	0.33

▸	CA7	P43166	2/20	0.33

▸	CA9	Q16790	2/20	0.33

▸	CA14	Q9ULX7	2/20	0.33

▸	CASP3	P42574	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29810959	0.90	SOS1 (0.40)	—
SCHEMBL25814978	0.89	TDP1 (0.36)	TDP1NPSR1TP53HTTPOLB
SCHEMBL29977115	0.89	TDP1 (0.36)	TDP1NPSR1TP53HTTPOLB
SCHEMBL26967275	0.84	TP53 (0.34)	TDP1NPSR1TP53HTTPOLB
SCHEMBL25820378	0.84	ALDH1A1 (0.40)	TDP1KDM4EKMT2AMAPTMEN1
SCHEMBL24616423	0.80	CFTR (0.34)	NPSR1HTTPOLBKDM4ELMNA
SCHEMBL24616284	0.78	SOS1 (0.36)	NPSR1HTTPOLBKDM4ELMNA
SCHEMBL29071023	0.78	TP53 (0.33)	TDP1NPSR1TP53HTTSMN1; SMN2
SCHEMBL26967480	0.77	CFTR (0.34)	NPSR1HTTPOLBSMN1; SMN2KDM4E
SCHEMBL31355666	0.77	SOS1 (0.36)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023125989-A1	QUINAZOLINE COMPOUND AND APPLICATION THEREOF	上海医药集团股份有限公司	2023-07-06	—	—	WO	disclosed