SCHEMBL2582072

SCHEMBL2582072

CCOC(=O)CC(N)CC(=O)OCC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.52
MGAM O43451 1/20 0.52
SI P14410 1/20 0.52
MGAM2 Q2M2H8 1/20 0.52
ALDH1A1 P00352 7/20 0.48
TRPA1 O75762 1/20 0.48
CYP1A2 P05177 1/20 0.46
ALOX15 P16050 3/20 0.46
CYP3A4 P08684 2/20 0.43
TSHR P16473 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
HSD17B10 Q99714 2/20 0.42
LMNA P02545 1/20 0.42
CHRM1 P11229 1/20 0.42
ADORA1 P30542 1/20 0.42
KDM4E B2RXH2 1/20 0.41
HTT P42858 1/20 0.41
SOAT1 P35610 1/20 0.40
CYP2D6 P10635 1/20 0.38
CA12 O43570 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3637939 0.98 GAA (0.50) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL3809171 0.91 MGAM (0.44) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL11124976 0.91 MGAM (0.44) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL14666206 0.91 GAA (0.44) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL11125234 0.91 MGAM (0.44) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL23155992 0.91 GAA (0.50) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL12057428 0.91 GAA (0.48) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL3989219 0.91 GAA (0.48) GAAMGAMSIMGAM2ALDH1A1
Hydrochloric Acid SCHEMBL7397037 0.89 MGAM (0.43) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL14593083 0.89 MGAM (0.46) GAAMGAMSIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008791-A1 CHEMICAL COMPOUNDS BORAH INC (US) 2026-01-08 US disclosed
EP-4648799-A1 LIGAND-DRUG CONJUGATES Sun Pharma Advanced Research Company Ltd (IN) 2025-11-19 EP disclosed
US-12358932-B2 Chemical compounds BORAH, INC. (US) 2025-07-15 US disclosed
US-20240368196-A1 CHEMICAL COMPOUNDS BORAH, INC. 2024-11-07 US disclosed
CN-114341145-B Chemical compound 博拉公司 2024-08-16 CN disclosed
WO-2024150132-A1 LIGAND-DRUG CONJUGATES SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) 2024-07-18 WO disclosed
EP-4374877-A2 PHARMACEUTICAL CONTAINING SODIUM-DEPENDENT PHOSPHATE TRANSPORTER INHIBITOR AND PHOSPHORUS ADSORBENT FOR USE IN THE PREVENTION, TREATMENT OR SUPPRESSION OF CHRONIC KIDNEY DISEASE, ARTERIOSCLEROSIS ASSOCIATED WITH VASCULAR CALCIFICATION, OR ECTOPIC CALCIFICATION. CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-05-29 EP disclosed
CN-118005917-A Gadolinium chelate and preparation method thereof and application thereof in preparation of magnetic resonance imaging contrast agent 南方医科大学 2024-05-10 CN disclosed
EP-3928779-B1 PHARMACEUTICAL CONTAINING SODIUM-DEPENDENT PHOSPHATE TRANSPORTER INHIBITOR AND PHOSPHORUS ADSORBENT FOR USE IN THE PREVENTION, TREATMENT OR SUPPRESSION OF CHRONIC KIDNEY DISEASE, ARTERIOSCLEROSIS ASSOCIATED WITH VASCULAR CALCIFICATION, OR ECTOPIC CALCIFICATION. CHUGAI PHARMACEUTICAL CO LTD (JP) 2024-03-06 EP disclosed
EP-3994142-A1 CHEMICAL COMPOUNDS Borah, Inc. (US) 2022-05-11 EP disclosed
WO-2011137135-A1 CHEMICAL COMPOUNDS GLAXOSMITHKLINE LLC (US) 2011-11-03 WO disclosed
US-7985424-B2 Dendritic polymers with enhanced amplification and interior functionality DENDRITIC NANOTECHNOLOGIES INC. (US) 2011-07-26 US disclosed
US-7985424-B2 Dendritic polymers with enhanced amplification and interior functionality DENDRITIC NANOTECHNOLOGIES INC. (US) 2011-07-26 US disclosed
US-7635784-B2 Process for the preparation of 3-amino-pentan-1,5-diol HOFFMANN-LA ROCHE INC. (US) 2009-12-22 US disclosed
US-20080312467-A1 NOVEL PROCESS FOR THE PREPARATION OF 3-AMINO-PENTAN-1,5-DIOL ROCHE CAROLINA INC. 2008-12-18 US disclosed
US-20070298006-A1 Dendritic Polymers With Enhanced Amplification and Interior Functionality DENDRITIC NANOTECHNOLOGIES, INC. (US) 2007-12-27 US disclosed
US-20070298006-A1 Dendritic Polymers With Enhanced Amplification and Interior Functionality DENDRITIC NANOTECHNOLOGIES, INC. (US) 2007-12-27 US disclosed
US-20040044225-A1 Chiral and achiral synthesis of 2-acyl substituted chromanes and their derivatives MILLENNIUM PHARMACEUTICALS, INC. 2004-03-04 US disclosed
WO-2001092249-A2 CHIRAL AND ACHIRAL SYNTHESIS OF 2-ACYL SUBSTITUTED CHROMANES AND THEIR DERIVATIVES COR THERAPEUTICS, INC. (US) 2001-12-06 WO disclosed
EP-0050799-A1 New processes for the production of di-alkyl esters and optically active mono-alkyl esters of 3-aminoglutaric acid ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1982-05-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008791-A1 CHEMICAL COMPOUNDS JAK3, JAK2, JAK1 GAA 2124/4885MGAM 4639/4885SI 4306/4885
US-20080312467-A1 NOVEL PROCESS FOR THE PREPARATION OF 3-AMINO-PENTAN-1,5-DIOL MAPK1, MAP3K1, MAP3K7 GAA 4654/4885MGAM 4357/4885SI 4113/4885
US-20040044225-A1 Chiral and achiral synthesis of 2-acyl substituted chromanes and their derivatives ACAT2, ACACA, COASY GAA 1871/4885MGAM 2480/4885SI 303/4885
US-20070298006-A1 Dendritic Polymers With Enhanced Amplification and Interior Functionality MYD88, TLR3, TMEM97 GAA 2744/4885MGAM 3760/4885SI 2757/4885
US-20240368196-A1 CHEMICAL COMPOUNDS PDE4A, PDE4B, SYK GAA 880/4885MGAM 3210/4885SI 3558/4885
US-12358932-B2 Chemical compounds PDE4A, PDE4B, SYK GAA 880/4885MGAM 3210/4885SI 3558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.