Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 2/20 | 0.46 |
| ▸ | DNMT3A | Q9Y6K1 | 2/20 | 0.46 |
| ▸ | CDK8 | P49336 | 2/20 | 0.45 |
| ▸ | CCNC | P24863 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | GAK | O14976 | 2/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.38 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30290923 | 0.95 | DNMT1 (0.43) | DNMT1DNMT3ACDK8CCNCGAA | |
| SCHEMBL24009942 | 0.95 | DNMT1 (0.43) | DNMT1DNMT3ACDK8CCNCGAA | |
| SCHEMBL25820779 | 0.90 | DNMT1 (0.42) | DNMT1DNMT3ACDK8CCNCGAA | |
| SCHEMBL25488283 | 0.86 | GAK (0.40) | DNMT1DNMT3ACDK8CCNCGAA | |
| SCHEMBL30290895 | 0.83 | DNMT1 (0.44) | DNMT1DNMT3ACDK8CCNCGAA | |
| SCHEMBL24010132 | 0.83 | DNMT1 (0.44) | DNMT1DNMT3ACDK8CCNCGAA | |
| SCHEMBL24006287 | 0.79 | DNMT1 (0.55) | DNMT1DNMT3ACDK8CCNCTGFBR1 | |
| SCHEMBL25820778 | 0.77 | ALDH1A1 (0.50) | GAAHTTALDH1A1 | |
| SCHEMBL25820678 | 0.77 | DNMT1 (0.62) | DNMT1DNMT3ACDK8CCNCTGFBR1 | |
| SCHEMBL24011122 | 0.77 | DNMT1 (0.68) | DNMT1DNMT3ACDK8CCNCTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | DNMT1 4335/4885DNMT3A 4603/4885CDK8 385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.