Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25488284 | 0.94 | ALDH1A1 (0.46) | ALDH1A1NPC1HTTTSHRGAA | |
| SCHEMBL25820779 | 0.88 | DNMT1 (0.42) | ALDH1A1HTTGAADHODHLMNA | |
| SCHEMBL25488283 | 0.82 | GAK (0.40) | ALDH1A1HTTGAABRAF | |
| SCHEMBL25820818 | 0.81 | UCHL1 (0.42) | ALDH1A1TSHRUCHL1 | |
| SCHEMBL25820804 | 0.78 | UCHL1 (0.45) | ALDH1A1HTTTSHRGAAUCHL1 | |
| SCHEMBL25820769 | 0.77 | DNMT1 (0.46) | ALDH1A1HTTGAA | |
| SCHEMBL24010364 | 0.75 | HTR2C (0.39) | ALDH1A1TSHRUCHL1 | |
| SCHEMBL25827157 | 0.74 | HTR2C (0.40) | HTTTSHRGAAUCHL1 | |
| SCHEMBL25820817 | 0.74 | UCHL1 (0.41) | ALDH1A1TSHRUCHL1 | |
| SCHEMBL30290923 | 0.73 | DNMT1 (0.43) | ALDH1A1HTTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | ALDH1A1 3871/4885NPC1 901/4885HTT 3124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.