Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2097650 | 0.79 | TDP1 (0.65) | TDP1GABRA1GABRG2GABRB3TP53 | |
| SCHEMBL8580636 | 0.77 | TDP1 (0.62) | TDP1GABRA1GABRG2GABRB3TP53 | |
| SCHEMBL109034 | 0.75 | TDP1 (0.60) | TDP1GABRA1GABRG2GABRB3TP53 | |
| SCHEMBL705623 | 0.75 | TDP1 (0.60) | TDP1GABRA1GABRG2GABRB3TP53 | |
| SCHEMBL7413769 | 0.75 | TDP1 (0.60) | TDP1GABRA1GABRG2GABRB3TP53 | |
| SCHEMBL7831326 | 0.75 | TDP1 (0.60) | TDP1GABRA1GABRG2GABRB3TP53 | |
| SCHEMBL7536038 | 0.75 | TDP1 (0.60) | TDP1GABRA1GABRG2GABRB3TP53 | |
| SCHEMBL7503380 | 0.75 | TDP1 (0.60) | TDP1GABRA1GABRG2GABRB3TP53 | |
| SCHEMBL11454521 | 0.75 | TDP1 (0.60) | TDP1GABRA1GABRG2GABRB3TP53 | |
| SCHEMBL128782 | 0.75 | TDP1 (0.60) | TDP1GABRA1GABRG2GABRB3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9562040-B2 | Processes for preparing Rivaroxaban | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2017-02-07 | — | — | US | claimed |
| EP-2899185-A1 | Processes for preparing linezolid | Indiana University Research and Technology Corporation (US) | 2015-07-29 | — | — | EP | claimed |
| US-20150175590-A1 | PROCESSES FOR PREPARING RIVAROXABAN | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION | 2015-06-25 | — | — | US | claimed |
| EP-2834235-A1 | PROCESSES FOR PREPARING RIVAROXABAN | Indiana University Research and Technology Corporation (US) | 2015-02-11 | — | — | EP | claimed |
| WO-2013152168-A1 | PROCESSES FOR PREPARING RIVAROXABAN | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2013-10-10 | — | — | WO | claimed |
| EP-2563781-A1 | PROCESSES FOR PREPARING LINEZOLID | Indiana University Research and Technology Corporation (US) | 2013-03-06 | — | — | EP | claimed |
| WO-2011137222-A1 | PROCESSES FOR PREPARING LINEZOLID | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2011-11-03 | — | — | WO | claimed |
| EP-2899185-B1 | Processes for preparing linezolid | UNIV INDIANA RES & TECH CORP (US) | 2018-01-31 | — | — | EP | disclosed |
| US-9656973-B2 | Processes for preparing linezolid | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2017-05-23 | — | — | US | disclosed |
| US-9562040-B2 | Processes for preparing Rivaroxaban | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2017-02-07 | — | — | US | disclosed |
| EP-2563781-B1 | PROCESSES FOR PREPARING LINEZOLID | UNIV INDIANA RES & TECH CORP (US) | 2016-10-26 | — | — | EP | disclosed |
| US-20160024032-A1 | PROCESSES FOR PREPARING LINEZOLID | UNIV INDIANA RES & TECH CORP (US) | 2016-01-28 | — | — | US | disclosed |
| US-9206141-B2 | Processes for preparing linezolid | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2015-12-08 | — | — | US | disclosed |
| EP-2899185-A1 | Processes for preparing linezolid | Indiana University Research and Technology Corporation (US) | 2015-07-29 | — | — | EP | disclosed |
| US-20150175590-A1 | PROCESSES FOR PREPARING RIVAROXABAN | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION | 2015-06-25 | — | — | US | disclosed |
| EP-2834235-A1 | PROCESSES FOR PREPARING RIVAROXABAN | Indiana University Research and Technology Corporation (US) | 2015-02-11 | — | — | EP | disclosed |
| WO-2013152168-A1 | PROCESSES FOR PREPARING RIVAROXABAN | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2013-10-10 | — | — | WO | disclosed |
| EP-2563781-A1 | PROCESSES FOR PREPARING LINEZOLID | Indiana University Research and Technology Corporation (US) | 2013-03-06 | — | — | EP | disclosed |
| US-20130053557-A1 | PROCESSES FOR PREPARING LINEZOLID | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2013-02-28 | — | — | US | disclosed |
| WO-2011137222-A1 | PROCESSES FOR PREPARING LINEZOLID | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2011-11-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150175590-A1 | PROCESSES FOR PREPARING RIVAROXABAN | VKORC1, VKORC1L1, CYP2C9 | TDP1 3478/4885GABRA1 1206/4885GABRG2 1076/4885 |
| US-20160024032-A1 | PROCESSES FOR PREPARING LINEZOLID | CYP2C9, CYP2C19, CYP3A43 | TDP1 4563/4885GABRA1 2416/4885GABRG2 1813/4885 |
| US-20130053557-A1 | PROCESSES FOR PREPARING LINEZOLID | CYP2C9, CYP2C19, CYP3A43 | TDP1 4563/4885GABRA1 2416/4885GABRG2 1813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.