Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 2/20 | 0.59 |
| ▸ | HTR1D | P28221 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | NSD2 | O96028 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.52 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3687411 | 0.92 | TSHR (0.61) | HTR1BTSHRKMT2AKDM4ENSD2 | |
| SCHEMBL8088241 | 0.89 | HTR1B (0.63) | HTR1BHTR1DTSHRKMT2AKDM4E | |
| SCHEMBL11663051 | 0.87 | TSHR (0.72) | TSHRKMT2ASMPD1GPBAR1PLA2G4B | |
| SCHEMBL25822229 | 0.86 | CYP1A2 (0.67) | HTR1BHTR1DKMT2AKDM4ENSD2 | |
| SCHEMBL4208924 | 0.85 | TSHR (0.76) | TSHRSMPD1GPBAR1PLA2G4BLTA4H | |
| SCHEMBL17138169 | 0.85 | TSHR (0.76) | TSHRSMPD1GPBAR1PLA2G4BLTA4H | |
| SCHEMBL6677146 | 0.85 | TSHR (0.76) | TSHRSMPD1GPBAR1PLA2G4BLTA4H | |
| SCHEMBL3905859 | 0.85 | TSHR (0.76) | TSHRSMPD1GPBAR1PLA2G4BLTA4H | |
| SCHEMBL17138159 | 0.85 | TSHR (0.76) | TSHRSMPD1GPBAR1PLA2G4BLTA4H | |
| SCHEMBL16699620 | 0.85 | TSHR (0.76) | TSHRSMPD1GPBAR1PLA2G4BLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | HTR1B 960/4885HTR1D 1401/4885TSHR 2971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.