Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GRM5 | P41594 | 5/20 | 0.52 |
| ▸ | BRAF | P15056 | 1/20 | 0.52 |
| ▸ | PYGL | P06737 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25822329 | 0.89 | MAPT (0.62) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL25822252 | 0.89 | SMN1; SMN2 (0.60) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL24010619 | 0.82 | GRM5 (0.55) | SMN1; SMN2RAB9ANPC1ALDH1A1GRM5 | |
| SCHEMBL25822220 | 0.80 | ALDH1A1 (0.50) | KMT2AMEN1MAPTLMNARAB9A | |
| SCHEMBL24010623 | 0.79 | GRM5 (0.54) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL25822054 | 0.78 | KMT2A (0.66) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL25822189 | 0.78 | BRAF (0.70) | KMT2AMEN1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL10090737 | 0.77 | ALDH1A1 (0.78) | KMT2AMEN1SMN1; SMN2LMNARAB9A | |
| SCHEMBL24010361 | 0.77 | GRM5 (0.54) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL25821722 | 0.77 | CYP1A2 (0.57) | KMT2AMEN1MAPTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | KMT2A 4131/4885MEN1 1172/4885MAPT 3976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.