Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.57 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.57 |
| ▸ | GRM5 | P41594 | 6/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | BRAF | P15056 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25822329 | 0.93 | MAPT (0.62) | SMN1; SMN2LMNAKMT2AGRM5MAPT | |
| SCHEMBL25822301 | 0.89 | KMT2A (0.57) | SMN1; SMN2LMNAKMT2AGRM5MAPT | |
| SCHEMBL25821902 | 0.85 | LMNA (0.70) | SMN1; SMN2LMNAKMT2APOLBCACNA1B | |
| SCHEMBL24010267 | 0.81 | GRM5 (0.60) | SMN1; SMN2LMNAGRM5RAB9ANPC1 | |
| SCHEMBL24010268 | 0.81 | GRM5 (0.59) | LMNAGRM5BRAF | |
| SCHEMBL30290826 | 0.81 | GRM5 (0.59) | LMNAGRM5BRAF | |
| SCHEMBL25822054 | 0.80 | KMT2A (0.66) | SMN1; SMN2LMNAKMT2APOLBCACNA1B | |
| SCHEMBL16963464 | 0.80 | KMT2A (0.69) | SMN1; SMN2LMNAKMT2APOLBCACNA1B | |
| SCHEMBL10090737 | 0.78 | ALDH1A1 (0.78) | SMN1; SMN2LMNAKMT2APOLBCACNA1B | |
| SCHEMBL7743046 | 0.78 | KMT2A (0.81) | SMN1; SMN2LMNAKMT2APOLBCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | SMN1; SMN2 2169/4885LMNA 2015/4885KMT2A 4131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.