Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28992052 | 0.83 | KDM4E (0.38) | PARP1KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL25822466 | 0.79 | MEN1 (0.38) | KDM4EMEN1KMT2AMAPTAPEX1 | |
| SCHEMBL13200125 | 0.76 | CYP1A2 (0.56) | KDM4ERAB9AMEN1KMT2AMAPT | |
| SCHEMBL20292636 | 0.75 | CYP1A2 (0.50) | PARP1KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL25820073 | 0.75 | PARP1 (0.38) | PARP1GABRA1GABRB2CDK2ALOX5AP | |
| SCHEMBL23046761 | 0.75 | TYMS (0.42) | KDM4ERAB9AMEN1KMT2AMAPT | |
| SCHEMBL25339154 | 0.74 | KDM4E (0.38) | PARP1KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL29941057 | 0.72 | NCF1 (0.53) | PARP1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL25846038 | 0.71 | MCHR1 (0.40) | PARP1MEN1KMT2AMAPTAPEX1 | |
| SCHEMBL25820060 | 0.71 | GAA (0.45) | KDM4EMEN1KMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | PARP1 2205/4885KDM4E 4219/4885RAB9A 1255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.