Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8114596 | 0.83 | DYRK1A (0.38) | GRM4DYRK1AKDM1ACHRNA7CYP2A6 | |
| SCHEMBL27265241 | 0.75 | CYP2A6 (0.37) | GRM4DYRK1AKDM1ACHRNA7CYP2A6 | |
| SCHEMBL17464091 | 0.75 | KDM1A (0.37) | GRM4DYRK1AKDM1ACHRNA7CYP2A6 | |
| SCHEMBL11724831 | 0.75 | CYP2A6 (0.47) | GRM4DYRK1AKDM1ACHRNA7CYP2A6 | |
| SCHEMBL26781843 | 0.71 | GRM4 (0.35) | GRM4DYRK1AKDM1ACHRNA7CYP2A6 | |
| SCHEMBL12749945 | 0.71 | KDM1A (0.35) | GRM4DYRK1AKDM1ACHRNA7CYP2A6 | |
| SCHEMBL27096937 | 0.71 | GRM4 (0.37) | GRM4DYRK1AKDM1ACHRNA7CYP2A6 | |
| SCHEMBL194366 | 0.71 | GRM4 (0.35) | GRM4DYRK1AKDM1ACHRNA7CYP2A6 | |
| SCHEMBL843122 | 0.69 | CHRNA7 (0.47) | CHRNA7KDM4EALDH1A1MAPT | |
| SCHEMBL11730253 | 0.69 | NPC1 (0.49) | GRM4KDM1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118234733-A | Five-membered heterocyclic pyrimidine derivatives and application thereof as pan KRAS mutation inhibitor | 思路迪生物医药(上海)有限公司 | 2024-06-21 | — | — | CN | disclosed |
| US-20230209989-A1 | ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME | LG DISPLAY CO., LTD. (KR) | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230209989-A1 | ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME | DDT, L3MBTL1, LAGE3 | GRM4 676/4885DYRK1A 2032/4885KDM1A 2395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.