Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18909494 | 0.75 | CYP19A1 (0.35) | CYP19A1 | |
| SCHEMBL19003073 | 0.73 | CYP19A1 (0.34) | CYP19A1 | |
| SCHEMBL9963714 | 0.70 | KMT2A (0.36) | CYP19A1 | |
| SCHEMBL12128404 | 0.68 | KMT2A (0.44) | — | |
| SCHEMBL22811534 | 0.68 | CYP19A1 (0.40) | CYP19A1 | |
| SCHEMBL21424522 | 0.68 | CYP19A1 (0.40) | CYP19A1 | |
| SCHEMBL104541 | 0.68 | — | — | |
| SCHEMBL17429857 | 0.67 | CYP19A1 (0.37) | CYP19A1 | |
| SCHEMBL18885103 | 0.67 | CYP19A1 (0.33) | CYP19A1 | |
| SCHEMBL19634091 | 0.67 | CYP19A1 (0.33) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227467-A1 | PHOSPHOINOSITIDE 3-KINASE INHIBITORS WITH A ZINC BINDING MOIETY | CURIS INC (US) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227467-A1 | PHOSPHOINOSITIDE 3-KINASE INHIBITORS WITH A ZINC BINDING MOIETY | BAZ2A, BAZ2B, PI4KB | CYP19A1 4441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.