⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30096746 | 1.00 | — | — | |
| SCHEMBL6882473 | 0.78 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL1606252 | 0.76 | — | — | |
| SCHEMBL11385334 | 0.76 | TSHR (0.39) | — | |
| SCHEMBL2864267 | 0.75 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL1332029 | 0.75 | — | — | |
| SCHEMBL453120 | 0.75 | SMN1; SMN2 (0.50) | — | |
| SCHEMBL270012 | 0.75 | — | — | |
| SCHEMBL2858771 | 0.74 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL27489759 | 0.74 | SMN1; SMN2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240270731-A1 | DEUTERATED COMPOUNDS | ALEBUND PHARMACEUTICALS (HONG KONG) LIMITED (CN) | 2024-08-15 | — | — | US | disclosed |
| EP-4384507-A1 | DEUTERATED COMPOUNDS | ALEBUND PHARMACEUTICALS (HONG KONG) LIMITED (HK) | 2024-06-19 | — | — | EP | disclosed |
| CN-116848095-B | Deuterated compounds | 礼邦生物医药(江苏)有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-115043799-B | Preparation method of 5, 6-dihydrobenzofuranone derivative | 南通大学 | 2024-02-23 | — | — | CN | disclosed |
| CN-116848095-A | Deuterated compounds | 礼邦医药(香港)有限公司 | 2023-10-03 | — | — | CN | disclosed |
| WO-2023016440-A1 | DEUTERATED COMPOUNDS | ALEBUND PHARMACEUTICALS (HONG KONG) LIMITED (CN) | 2023-02-16 | — | — | WO | disclosed |
| WO-2023016440-A1 | DEUTERATED COMPOUNDS | ALEBUND PHARMACEUTICALS (HONG KONG) LIMITED (CN) | 2023-02-16 | — | — | WO | disclosed |
| CN-115043799-A | Preparation method of 5, 6-dihydrobenzofuranone derivative | 南通大学 | 2022-09-13 | — | — | CN | disclosed |
| CN-114874167-A | Preparation method of 5-hydroxyfuranone derivative | 南通大学 | 2022-08-09 | — | — | CN | disclosed |
| US-10221137-B2 | Herbicidal phenylpyridines | BASF SE (DE) | 2019-03-05 | — | — | US | disclosed |
| US-20050070714-A1 | Process for the production of chiral propionic acid derivatives | HOFFMANN-LA ROCHE INC. | 2005-03-31 | — | — | US | disclosed |
| US-20040147585-A1 | Method for the synthesis of Soritin compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-07-29 | — | — | US | disclosed |
| EP-0835252-B1 | TRIAZOLE ANTIFUNGAL AGENTS | PFIZER RES & DEV (IE) | 2003-07-30 | — | — | EP | disclosed |
| US-20020037875-A1 | Alpha-amino,-thio,-oxo substituted ketones as phospholipase inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2002-03-28 | — | — | US | disclosed |
| US-6015825-A | Triazole antifungal agents | PFIZER INC. (US) | 2000-01-18 | — | — | US | disclosed |
| EP-0835252-A1 | TRIAZOLE ANTIFUNGAL AGENTS | Pfizer Research and Development Company, N.V./S.A. (IE) | 1998-04-15 | — | — | EP | disclosed |
| WO-1997001552-A1 | TRIAZOLE ANTIFUNGAL AGENTS | PFIZER RESEARCH AND DEVELOPMENT COMPANY, N.V./S.A. (IE) | 1997-01-16 | — | — | WO | disclosed |
| US-4399131-A | Cephem derivatives | HOECHST AG (DE) | 1983-08-16 | — | — | US | disclosed |
| EP-0022626-A1 | Substituted nitrodiphenyl ethers, herbicidal compositions containing them and method of combating weeds | ROHM AND HAAS COMPANY (US) | 1981-01-21 | — | — | EP | disclosed |
| US-3962224-A | CHEMICAL INTERMEDIATES FOR ANTIBIOTICS | MERCK & CO., INC. (US) | 1976-06-08 | — | — | US | disclosed |