SCHEMBL453120

SCHEMBL453120

COC(=O)C(Cl)C(=O)OC

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.50
CA14 Q9ULX7 2/20 0.40
ALDH1A1 P00352 3/20 0.39
KMT2A Q03164 2/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
TSHR P16473 2/20 0.33
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
ZDHHC7 Q9NXF8 1/20 0.33
LMNA P02545 1/20 0.32
MGAM O43451 2/20 0.30
GAA P10253 2/20 0.30
SI P14410 2/20 0.30
MGAM2 Q2M2H8 2/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7944709 0.89
SCHEMBL269783 0.85
SCHEMBL4110912 0.85
SCHEMBL6527167 0.85
SCHEMBL18098644 0.84 MGAM (0.44) SMN1; SMN2ALDH1A1KMT2ACA1CA2
SCHEMBL28347464 0.83 SMN1; SMN2 (0.40) SMN1; SMN2CA14ALDH1A1KMT2ACA12
SCHEMBL7583623 0.81 SMN1; SMN2 (0.39) SMN1; SMN2CA14ALDH1A1KMT2ACA12
SCHEMBL11408274 0.81 SMN1; SMN2 (0.39) SMN1; SMN2CA14ALDH1A1KMT2ACA12
SCHEMBL1332029 0.80
SCHEMBL2864267 0.80 SMN1; SMN2 (0.48) SMN1; SMN2CA14ALDH1A1KMT2ACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 328 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552902-B2 Composition for optical material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2026-02-17 US claimed
CN-119342971-A ABX (ABX)3Metal halide perovskite film, preparation method and photovoltaic device 南京工业大学 2025-01-21 CN claimed
CN-118222769-A Multi-carboxylic acid group high-absorption chrome tanning auxiliary agent containing barbituric acid structure and preparation method thereof 南京工业大学 2024-06-21 CN claimed
CN-118186152-A Multifunctional high-absorption chrome tanning auxiliary agent containing barbituric acid structure and preparation method thereof 南京工业大学 2024-06-14 CN claimed
CN-115667369-B Composition for optical material 三菱瓦斯化学株式会社 2024-04-05 CN claimed
CN-117106294-A Medical packaging bottle plastic material and preparation method thereof 沧州维康食品药品包装有限公司 2023-11-24 CN claimed
CN-114539048-B Carlong anhydride intermediate and preparation method of Carlong anhydride 新发药业有限公司 2023-09-08 CN claimed
EP-4160279-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-04-05 EP claimed
US-20230100848-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-03-30 US claimed
CN-115732783-A Composite metal lithium cathode with artificial solid electrolyte interface layer and preparation method and application thereof 电子科技大学长三角研究院(湖州) 2023-03-03 CN claimed
CN-113072505-B Preparation method of pentadeuterium atom substituted 2-thiophenobarbital 中国科学院成都有机化学有限公司 2022-07-19 CN claimed
CN-114539048-A Caronic anhydride intermediate and preparation method of caronic anhydride 新发药业有限公司 2022-05-27 CN claimed
CN-114375964-A Binary compound weeding composition containing anilofos and preparation method thereof 合肥巨卓农业技术开发有限公司 2022-04-22 CN claimed
CN-113072505-A Preparation method of pentadeuterium atom substituted 2-thiophenobarbital 中国科学院成都有机化学有限公司 2021-07-06 CN claimed
CN-109824512-A A kind of preparation method of 2- fluorine dimethyl malenate 国药集团化学试剂有限公司 2019-05-31 CN claimed
CN-116507610-B Herbicidal malonamides 巴斯夫欧洲公司 2026-05-19 CN disclosed
CN-122055351-A Process for the production of 2-methoxy malonate 巴斯夫欧洲公司 2026-05-15 CN disclosed
EP-0601386-A1 Sulphonamides F. HOFFMANN-LA ROCHE AG (CH) 1994-06-15 EP disclosed
EP-0526708-A1 Sulfonamide, preparation and use thereof as medicine and intermediate F. HOFFMANN-LA ROCHE AG (CH) 1993-02-10 EP disclosed
US-4046759-A INTERMEDIATES FOR CEPHALOSPORINS ISHIMARU TOSHIYASU 1977-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552902-B2 Composition for optical material PAX2, RPL21, PAXBP1 SMN1; SMN2 4678/4885CA14 1431/4885ALDH1A1 1088/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.