Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.38 |
| ▸ | CTH | P32929 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8171745 | 0.89 | EGFR (0.48) | EGFRPIM1ELANEMEN1KMT2A | |
| SCHEMBL13444092 | 0.89 | EGFR (0.48) | EGFRPIM1ELANEMEN1KMT2A | |
| SCHEMBL23022615 | 0.89 | EGFR (0.48) | EGFRPIM1ELANEMEN1KMT2A | |
| SCHEMBL16848014 | 0.88 | EGFR (0.47) | EGFRPIM1ELANEMEN1KMT2A | |
| SCHEMBL19789618 | 0.88 | EGFR (0.47) | EGFRPIM1ELANEMEN1KMT2A | |
| SCHEMBL23022613 | 0.87 | ELANE (0.47) | EGFRPIM1ELANEMEN1KMT2A | |
| SCHEMBL23022621 | 0.86 | EGFR (0.46) | EGFRPIM1ELANEMEN1KMT2A | |
| SCHEMBL22873368 | 0.86 | EGFR (0.51) | EGFRPIM1ELANEMEN1KMT2A | |
| SCHEMBL21886965 | 0.86 | EGFR (0.51) | EGFRPIM1ELANEMEN1KMT2A | |
| SCHEMBL11395596 | 0.86 | EGFR (0.51) | EGFRPIM1ELANEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154594-B1 | FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO | BACH BIOSCIENCES LLC (US) | 2023-07-19 | — | — | EP | disclosed |