SCHEMBL25823972 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	BRPF1	P55201	3/20	0.42

▸	BRD1	O95696	2/20	0.42

▸	BRD4	O60885	1/20	0.42

▸	BRPF3	Q9ULD4	1/20	0.42

▸	HTR2C	P28335	10/20	0.40

▸	HTR2B	P41595	8/20	0.40

▸	RAD52	P43351	1/20	0.38

▸	LATS1	O95835	1/20	0.38

▸	HTR2A	P28223	8/20	0.38

▸	HTR6	P50406	1/20	0.36

▸	ALDH1A1	P00352	1/20	0.36

▸	SMN1; SMN2	Q16637	1/20	0.36

▸	SPAST	Q9UBP0	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL22542060	0.83	BRPF1 (0.47)	BRPF1BRD1BRD4BRPF3HTR2C
SCHEMBL22542057	0.83	BRPF1 (0.47)	BRPF1BRD1BRD4BRPF3HTR2C
SCHEMBL21359240	0.82	HTR2C (0.47)	BRPF1BRD1BRD4BRPF3HTR2C
SCHEMBL19709395	0.82	HTR3E (0.51)	BRPF1BRD1BRD4BRPF3HTR2C
SCHEMBL30952461	0.82	HTR2C (0.47)	BRPF1BRD1BRD4BRPF3HTR2C
SCHEMBL19709331	0.82	HTR2C (0.47)	BRPF1BRD1BRD4BRPF3HTR2C
SCHEMBL21359242	0.82	HTR2C (0.47)	BRPF1BRD1BRD4BRPF3HTR2C
SCHEMBL4196575	0.82	NR4A1 (0.46)	BRPF1BRD1BRD4BRPF3HTR2C
SCHEMBL20884982	0.80	BRPF1 (0.42)	BRPF1BRD1BRD4BRPF3HTR2C
SCHEMBL20883819	0.80	BRPF1 (0.42)	BRPF1BRD1BRD4BRPF3HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023125944-A1	COMPOUND CONTAINING HETEROCYCLIC RING	正大天晴药业集团股份有限公司	2023-07-06	—	—	WO	disclosed