Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4832834 | 0.96 | LOXL2 (0.49) | LOXL2LTA4HKDM4EALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL4935323 | 0.94 | LOXL2 (0.48) | LOXL2LTA4HKDM4EALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL27836123 | 0.91 | LOXL2 (0.50) | LOXL2LTA4HKDM4EALDH1A1GAA | |
| SCHEMBL24675766 | 0.90 | CNR1 (0.47) | LOXL2LTA4HKDM4EALDH1A1GAA | |
| SCHEMBL25823996 | 0.90 | CNR1 (0.47) | LOXL2LTA4HKDM4EALDH1A1GAA | |
| SCHEMBL24675794 | 0.90 | CNR1 (0.47) | LOXL2LTA4HKDM4EALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL25249852 | 0.89 | CNR1 (0.47) | LOXL2LTA4HKDM4EALDH1A1GAA | |
| SCHEMBL24674879 | 0.87 | CNR1 (0.45) | LOXL2KDM4EALDH1A1GAAPOLB | |
| SCHEMBL7413008 | 0.87 | SMN1; SMN2 (0.49) | LTA4HKDM4EALDH1A1GAAHPGD | |
| SCHEMBL8279857 | 0.86 | CYSLTR2 (0.54) | LTA4HMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465811-B2 | Indoline compounds | LABORATOIRES FOURNIER S.A. (FR) | 2008-12-16 | — | — | US | disclosed |
| US-20080119465-A1 | Novel Indoline Compounds | LABORATORIES FOURNIER S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119465-A1 | Novel Indoline Compounds | GPR119, INSR, IRS1 | LOXL2 4346/4885LTA4H 1742/4885KDM4E 1574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.