Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 3/20 | 0.77 |
| ▸ | P2RY6 | Q15077 | 5/20 | 0.62 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.62 |
| ▸ | TK2 | O00142 | 2/20 | 0.54 |
| ▸ | TK1 | P04183 | 1/20 | 0.51 |
| ▸ | ADK | P55263 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | HBB | P68871 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6839765 | 0.91 | PYGM (0.82) | PYGMP2RY6P2RY14TK2TK1 | |
| SCHEMBL3412420 | 0.88 | PYGM (0.97) | PYGMP2RY6P2RY14TK2TK1 | |
| SCHEMBL2579194 | 0.88 | PYGM (0.97) | PYGMP2RY6P2RY14TK2TK1 | |
| SCHEMBL2056544 | 0.88 | PYGM (0.97) | PYGMP2RY6P2RY14TK2TK1 | |
| SCHEMBL97336 | 0.88 | PYGM (0.97) | PYGMP2RY6P2RY14TK2TK1 | |
| SCHEMBL12315567 | 0.88 | PYGM (0.97) | PYGMP2RY6P2RY14TK2TK1 | |
| SCHEMBL3389861 | 0.88 | PYGM (0.97) | PYGMP2RY6P2RY14TK2TK1 | |
| SCHEMBL2056540 | 0.88 | PYGM (0.97) | PYGMP2RY6P2RY14TK2TK1 | |
| SCHEMBL654674 | 0.88 | PYGM (0.97) | PYGMP2RY6P2RY14TK2TK1 | |
| SCHEMBL97335 | 0.88 | PYGM (0.97) | PYGMP2RY6P2RY14TK2TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |