Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27054129 | 0.91 | TK1 (0.59) | TYMS | |
| SCHEMBL27060411 | 0.91 | TK1 (0.59) | TYMS | |
| SCHEMBL24420691 | 0.91 | TK1 (0.59) | TYMS | |
| SCHEMBL24420689 | 0.89 | RNASE1 (0.43) | TYMS | |
| SCHEMBL25824058 | 0.86 | TK1 (0.54) | — | |
| SCHEMBL27054126 | 0.82 | RNASE1 (0.44) | TYMS | |
| SCHEMBL27058612 | 0.82 | RNASE1 (0.44) | TYMS | |
| SCHEMBL23215242 | 0.81 | TYMS (0.53) | TYMS | |
| SCHEMBL29011226 | 0.78 | TK1 (0.58) | TYMS | |
| SCHEMBL17279676 | 0.78 | TK1 (0.57) | TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |