Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | MGAM | O43451 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779879 | 1.00 | PTGS1 (0.57) | PTGS1MGAMMAOAMAOBCYP3A4 | |
| SCHEMBL29618998 | 1.00 | PTGS1 (0.57) | PTGS1MGAMMAOAMAOBCYP3A4 | |
| SCHEMBL29682883 | 1.00 | PTGS1 (0.57) | PTGS1MGAMMAOAMAOBCYP3A4 | |
| SCHEMBL29480609 | 1.00 | PTGS1 (0.57) | PTGS1MGAMMAOAMAOBCYP3A4 | |
| SCHEMBL29618999 | 1.00 | PTGS1 (0.57) | PTGS1MGAMMAOAMAOBCYP3A4 | |
| SCHEMBL29682579 | 1.00 | PTGS1 (0.57) | PTGS1MGAMMAOAMAOBCYP3A4 | |
| SCHEMBL29480585 | 0.87 | MAPT (0.60) | PTGS1MGAMMAOAMAOBCYP3A4 | |
| SCHEMBL30554025 | 0.85 | PTGS1 (0.55) | PTGS1MAOAMAOBCYP3A4MAPT | |
| SCHEMBL21168205 | 0.80 | MAOA (0.64) | PTGS1MGAMMAOAMAOBCYP3A4 | |
| SCHEMBL31237248 | 0.80 | MAOA (0.64) | PTGS1MGAMMAOAMAOBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130150-A2 | SYSTEMS, CELL LINES AND METHODS OF PRODUCING AND USING THE SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-07-06 | — | — | WO | disclosed |