Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25823793 | 0.80 | TNKS (0.36) | TNKSTNKS2P2RX3MEN1LMNA | |
| SCHEMBL25824839 | 0.75 | TLR7 (0.45) | — | |
| SCHEMBL28671352 | 0.74 | PDE4A (0.46) | TNKSTNKS2P2RX3MEN1LMNA | |
| SCHEMBL28840194 | 0.70 | DAO (0.30) | — | |
| SCHEMBL7688428 | 0.70 | LMNA (0.56) | TNKSTNKS2P2RX3MEN1LMNA | |
| SCHEMBL21118430 | 0.70 | FDPS (0.39) | MEN1LMNAKMT2A | |
| SCHEMBL26653370 | 0.69 | CYP1A2 (0.33) | MEN1LMNAKMT2A | |
| SCHEMBL23240599 | 0.69 | TNKS (0.36) | TNKSTNKS2P2RX3MEN1LMNA | |
| SCHEMBL25826053 | 0.68 | TLR7 (0.46) | — | |
| SCHEMBL23202176 | 0.68 | LMNA (0.37) | TNKSTNKS2P2RX3MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |