Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | USP1 | O94782 | 7/20 | 0.36 |
| ▸ | RORC | P51449 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.34 |
| ▸ | CDK2 | P24941 | 3/20 | 0.34 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2571383 | 0.86 | PTGDR2 (0.68) | PTGDR2USP1RORCSCN9A | |
| SCHEMBL2571346 | 0.84 | PTGDR2 (0.58) | PTGDR2USP1RORCSCN9A | |
| SCHEMBL2574953 | 0.82 | PTGDR2 (0.44) | PTGDR2RORCDCTPP1SCN9ANOTUM | |
| SCHEMBL2568500 | 0.77 | PTGDR2 (0.81) | PTGDR2USP1RORCCCNE1CDK2 | |
| SCHEMBL2570635 | 0.77 | RORC (0.37) | PTGDR2USP1RORCCCNE1CDK2 | |
| SCHEMBL2574616 | 0.75 | PTGDR2 (0.69) | PTGDR2USP1RORCCCNE1CDK2 | |
| SCHEMBL27780421 | 0.75 | PTGDR2 (0.41) | PTGDR2USP1RORCCCNE1CDK2 | |
| SCHEMBL2581536 | 0.75 | RORC (0.47) | RORC | |
| SCHEMBL27893548 | 0.75 | PTGDR2 (0.42) | PTGDR2USP1RORCCCNE1CDK2 | |
| SCHEMBL2576343 | 0.74 | PTGDR2 (0.39) | PTGDR2USP1RORCPOLBCCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139881-B1 | QUINOLINES AND THEIR THERAPEUTIC USE | PULMAGEN THERAPEUTICS ASTHMA LTD (GB) | 2011-11-09 | — | — | EP | claimed |