Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2574953 | 0.89 | PTGDR2 (0.44) | RORC | |
| SCHEMBL2585815 | 0.89 | PTGDR2 (0.46) | RORC | |
| SCHEMBL2575125 | 0.84 | PTGDR2 (0.52) | RORCADRA2BPPARGPPARDNR1H3 | |
| SCHEMBL2568427 | 0.83 | RORC (0.48) | RORCADRA2BPPARGPPARDNR1H3 | |
| SCHEMBL2577124 | 0.79 | PTGDR2 (0.54) | RORC | |
| SCHEMBL2573811 | 0.75 | PTGDR2 (0.52) | RORCADRA2BPPARGPPARDNR1H3 | |
| SCHEMBL2582465 | 0.75 | PTGDR2 (0.48) | RORC | |
| SCHEMBL2577052 | 0.74 | PTGDR2 (0.61) | RORCADRA2BPPARGPPARDNR1H3 | |
| SCHEMBL2579240 | 0.74 | PTGDR2 (0.34) | — | |
| SCHEMBL2574222 | 0.74 | RORC (0.40) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139881-B1 | QUINOLINES AND THEIR THERAPEUTIC USE | PULMAGEN THERAPEUTICS ASTHMA LTD (GB) | 2011-11-09 | — | — | EP | claimed |