SCHEMBL25824711

SCHEMBL25824711

Clc1ccc2cc(-c3ccc4ccccc4c3)oc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.52
ALOX5 P09917 1/20 0.49
MAOB P27338 2/20 0.47
MAOA P21397 1/20 0.45
SHBG P04278 1/20 0.45
PTPN1 P18031 2/20 0.44
PTPRC P08575 1/20 0.44
CYP1A2 P05177 3/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CYP1A1 P04798 3/20 0.43
CYP1B1 Q16678 3/20 0.43
TNKS O95271 2/20 0.43
CYP11B1 P15538 1/20 0.42
CYP11B2 P19099 1/20 0.42
MIF P14174 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
GABRP O00591 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25825140 0.86 GABRP (0.49) CYP2A6ALOX5MAOBMAOASHBG
SCHEMBL6583412 0.84 ALOX5 (0.66) ALOX5MAOBMAOASHBGPTPN1
SCHEMBL19887207 0.83 GABRP (0.58) MAOBMAOASHBGPTPN1CYP1A2
SCHEMBL19683686 0.81 NPC1 (0.47) CYP2A6MAOBSHBGPTPN1SMN1; SMN2
SCHEMBL11613110 0.79 MAOB (0.68) ALOX5MAOBMAOASHBGPTPN1
SCHEMBL11733704 0.78 KCNA5 (0.62) MAOBPTPN1SMN1; SMN2TNKSCA1
SCHEMBL29939110 0.77 MAOB (0.66) ALOX5MAOBMAOAPTPN1PTPRC
SCHEMBL26103640 0.77 MAOB (0.66) ALOX5MAOBMAOAPTPN1PTPRC
SCHEMBL29182290 0.76 MAOB (0.65) ALOX5MAOBMAOAPTPN1PTPRC
SCHEMBL31290937 0.76 MAOB (0.65) ALOX5MAOBMAOAPTPN1PTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023132488-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-07-13 WO disclosed