Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TNNI3K | Q59H18 | 10/20 | 0.43 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25820335 | 0.85 | GFER (0.46) | CHRNA7SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL5700409 | 0.80 | CHRNA7 (0.46) | CHRNA7GCK | |
| SCHEMBL14299655 | 0.79 | CHRNA7 (0.58) | CHRNA7LMNACA12CA1CA2 | |
| SCHEMBL25463208 | 0.77 | LMNA (0.50) | L3MBTL1TNNI3KEGFRLMNASMN1; SMN2 | |
| SCHEMBL15392663 | 0.75 | CA12 (0.50) | L3MBTL1TNNI3KEGFRLMNASMN1; SMN2 | |
| SCHEMBL24221424 | 0.71 | CHRNA7 (0.45) | CHRNA7GAACA1CA2BRAF | |
| SCHEMBL17107863 | 0.70 | SMN1; SMN2 (0.42) | L3MBTL1LMNASMN1; SMN2GAACA12 | |
| SCHEMBL23015739 | 0.69 | ALDH1A1 (0.43) | L3MBTL1CHRNA7LMNASMN1; SMN2HTT | |
| SCHEMBL5234953 | 0.69 | SMN1; SMN2 (0.58) | L3MBTL1LMNASMN1; SMN2GAACA12 | |
| SCHEMBL20889919 | 0.68 | GRIN2D (0.36) | EGFRCHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | L3MBTL1 3768/4885TNNI3K 237/4885EGFR 1176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.