SCHEMBL25825247

SCHEMBL25825247

Cc1cccc2c1[nH]c1cc3ccccc3cc12

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.65
KDM4E B2RXH2 1/20 0.49
AHR P35869 1/20 0.47
ALDH1A1 P00352 4/20 0.46
MAPT P10636 3/20 0.46
POLB P06746 2/20 0.46
GAA P10253 2/20 0.46
RXFP1 Q9HBX9 1/20 0.46
CYP2A6 P11509 1/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
PCSK9 Q8NBP7 1/20 0.43
RPA1 P27694 1/20 0.43
MCL1 Q07820 1/20 0.43
OPRM1 P35372 1/20 0.42
OPRD1 P41143 1/20 0.42
UHRF1 Q96T88 1/20 0.42
ABCB1 P08183 1/20 0.41
JAK2 O60674 1/20 0.41
RAD52 P43351 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25693505 0.81 KIF11 (0.62) KIF11KDM4EAHRALDH1A1MAPT
SCHEMBL17775035 0.81 KIF11 (0.55) KIF11KDM4EAHRALDH1A1MAPT
SCHEMBL20934355 0.79 KIF11 (0.66) KIF11KDM4EAHRALDH1A1MAPT
SCHEMBL15848721 0.79 KIF11 (0.51) KIF11KDM4EAHRALDH1A1MAPT
SCHEMBL27915 0.79 KIF11 (1.00) KIF11KDM4EAHRALDH1A1MAPT
SCHEMBL29412284 0.79 KIF11 (1.00) KIF11KDM4EAHRALDH1A1MAPT
SCHEMBL24561302 0.79 KIF11 (0.42) KIF11KDM4EAHRMAPTMEN1
SCHEMBL22026626 0.79 CCNE2 (0.43) KIF11KDM4EAHRMAPTMEN1
SCHEMBL21448184 0.79 DYRK1A (0.50) KIF11KDM4EAHRMAPTCYP2A6
SCHEMBL30180883 0.79 DYRK1A (0.50) KIF11KDM4EAHRMAPTCYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4265624-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME Lg Chem, Ltd. (KR) 2023-10-25 EP disclosed
US-20230203054-A1 ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, THIN FILM, LIGHT-EMITTING APPARATUS, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230203054-A1 ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, THIN FILM, LIGHT-EMITTING APPARATUS, ELECTRONIC DEVICE, AND LIGHTING DEVICE AHR, CYP1A1, CRY1 KIF11 3753/4885KDM4E 1611/4885AHR 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.