SCHEMBL25825360

SCHEMBL25825360

Brc1c2ccccc2cc2cc(-c3ccccc3)ccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.55
GRIN2A Q12879 1/20 0.55
GRIN2B Q13224 1/20 0.55
GRIN2C Q14957 1/20 0.55
HSD17B1 P14061 4/20 0.47
HSD17B2 P37059 4/20 0.47
ESR1 P03372 7/20 0.47
ESR2 Q92731 7/20 0.47
ALDH1A1 P00352 3/20 0.41
MAPK1 P28482 1/20 0.41
CYP19A1 P11511 1/20 0.40
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40
GPR84 Q9NQS5 1/20 0.40
CYP1A2 P05177 2/20 0.39
CYP2C19 P33261 2/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2B6 P20813 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1527510 0.91 GRIN2D (0.54) GRIN2DGRIN2AGRIN2BGRIN2CHSD17B1
Biphenyl SCHEMBL13719514 0.90 ALDH1A1 (0.45) GRIN2DGRIN2AGRIN2BGRIN2CESR1
SCHEMBL13147477 0.89 GRIN2D (0.44) GRIN2DGRIN2AGRIN2BGRIN2CHSD17B1
Benzene SCHEMBL2725663 0.83 ALDH1A1 (0.50) ALDH1A1CYP1A2CYP2C19CYP3A4KDM4E
SCHEMBL27616568 0.82 ESR1 (0.57) GRIN2DGRIN2AGRIN2BGRIN2CHSD17B1
SCHEMBL18422834 0.82 ESR1 (0.50) GRIN2DGRIN2AGRIN2BGRIN2CHSD17B1
SCHEMBL29527767 0.81 POLB (0.52) ALDH1A1MAPK1CYP1A2CYP2C19CYP3A4
SCHEMBL132836 0.81 POLB (0.52) ALDH1A1MAPK1CYP1A2CYP2C19CYP3A4
SCHEMBL27858229 0.81 ESR1 (0.47) HSD17B1HSD17B2ESR1ESR2ALDH1A1
SCHEMBL28543785 0.80 ESR1 (0.44) GRIN2DGRIN2AGRIN2BGRIN2CHSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023132488-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-07-13 WO disclosed