SCHEMBL28543785

SCHEMBL28543785

OB(O)c1c2ccccc2cc2cc(-c3ccccc3)ccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.44
ESR2 Q92731 6/20 0.44
HSD17B1 P14061 4/20 0.44
HSD17B2 P37059 4/20 0.44
MGLL Q99685 2/20 0.43
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
GRIN2D O15399 1/20 0.41
GRIN2A Q12879 1/20 0.41
GRIN2B Q13224 1/20 0.41
GRIN2C Q14957 1/20 0.41
GPR84 Q9NQS5 2/20 0.40
PLG P00747 1/20 0.40
F12 P00748 1/20 0.40
F11 P03951 1/20 0.40
KLKB1 P03952 1/20 0.40
PRSS1 P07477 1/20 0.40
PRSS2 P07478 1/20 0.40
PRSS3 P35030 1/20 0.40
CYP1A2 P05177 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19195016 0.92 ESR1 (0.46) ESR1ESR2HSD17B1HSD17B2MGLL
SCHEMBL22534564 0.90 MGLL (0.43) ESR1ESR2HSD17B1HSD17B2MGLL
Benzene SCHEMBL5134896 0.85 ALDH1A1 (0.50) MGLLCA1CA2CYP1A2CYP2C19
SCHEMBL24958 0.83 HSD17B10 (0.46) MGLLCA1CA2CYP1A2CYP2C19
SCHEMBL29414927 0.83 HSD17B10 (0.46) MGLLCA1CA2CYP1A2CYP2C19
SCHEMBL25825360 0.80 GRIN2D (0.55) ESR1ESR2HSD17B1HSD17B2GRIN2D
SCHEMBL27616568 0.78 ESR1 (0.57) ESR1ESR2HSD17B1HSD17B2GRIN2D
SCHEMBL29643193 0.78 ESR1 (0.49) ESR1ESR2HSD17B1HSD17B2MGLL
SCHEMBL1527511 0.78 ESR1 (0.49) ESR1ESR2HSD17B1HSD17B2MGLL
SCHEMBL4638941 0.78 ALDH1A1 (0.42) HSD17B1HSD17B2MGLLCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112592308-A Novel organic compound and application thereof in OLED device 北京燕化集联光电技术有限公司 2021-04-02 CN disclosed