Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2207464 | 0.90 | TDP1 (0.60) | NR1H3TDP1L3MBTL1GPR84OPRM1 | |
| SCHEMBL15956399 | 0.86 | TDP1 (0.68) | NR1H3TDP1L3MBTL1GPR84OPRM1 | |
| SCHEMBL7886506 | 0.82 | NR1H3 (0.62) | NR1H3TDP1L3MBTL1GPR84OPRM1 | |
| SCHEMBL5158373 | 0.75 | KDM4E (0.54) | TDP1L3MBTL1ALDH1A1TSHRMAPK1 | |
| SCHEMBL15955998 | 0.75 | TDP1 (0.67) | TDP1L3MBTL1GPR84POLBCYP1B1 | |
| SCHEMBL14092273 | 0.74 | TDP1 (0.66) | NR1H3TDP1L3MBTL1GPR84ALDH1A1 | |
| SCHEMBL2157305 | 0.73 | TDP1 (0.60) | TDP1L3MBTL1ALDH1A1ALDH2PKM | |
| SCHEMBL10352124 | 0.73 | TDP1 (0.60) | TDP1L3MBTL1ALDH1A1ALDH2PKM | |
| SCHEMBL14044517 | 0.73 | TDP1 (0.60) | TDP1L3MBTL1ALDH1A1ALDH2PKM | |
| SCHEMBL2754682 | 0.73 | CYP1B1 (0.61) | TDP1L3MBTL1ALDH1A1ALDH2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | NR1H3 121/4885TDP1 529/4885L3MBTL1 2438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.