Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13956958 | 0.81 | KMT2A (0.45) | KMT2AALDH1A1NPSR1MEN1GFER | |
| SCHEMBL7916957 | 0.79 | SMN1; SMN2 (0.58) | KMT2AALDH1A1MEN1SMN1; SMN2POLB | |
| SCHEMBL15573994 | 0.79 | NPSR1 (0.42) | KMT2AALDH1A1NPSR1MEN1GFER | |
| SCHEMBL12414645 | 0.78 | CHRNA7 (0.47) | CHRNA7ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL20692252 | 0.78 | CHRNA7 (0.42) | KMT2ACHRNA7ALDH1A1SMN1; SMN2CA1 | |
| SCHEMBL16172616 | 0.77 | ALDH1A1 (0.44) | CHRNA7ALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL15574004 | 0.77 | KDM4E (0.63) | KMT2AALDH1A1NPSR1MEN1GFER | |
| SCHEMBL14299649 | 0.77 | CHRNA7 (0.60) | CHRNA7ALDH1A1CA12CA1CA2 | |
| SCHEMBL12695033 | 0.77 | CHRNA7 (0.46) | CHRNA7ALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL15575098 | 0.76 | SLC40A1 (0.49) | KMT2AALDH1A1NPSR1MEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | KMT2A 3974/4885CHRNA7 4724/4885ALDH1A1 4541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.