Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 3/20 | 0.33 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23114318 | 0.84 | CHRNA7 (0.40) | PANK3CHRNA7ESR1ESR2NR1H2 | |
| SCHEMBL24837402 | 0.81 | ESR1 (0.38) | PANK3CHRNA7ESR1ESR2NR1H2 | |
| SCHEMBL25820317 | 0.75 | CHRNA7 (0.39) | CHRNA7NR1H2ALOX5APFEN1PIK3CA | |
| SCHEMBL5513354 | 0.74 | GABRP (0.56) | PANK3ESR1ESR2SLC22A12CPB2 | |
| SCHEMBL24760247 | 0.74 | PANK3 (0.47) | PANK3ESR1ESR2NR1H2NR1H3 | |
| SCHEMBL5513086 | 0.74 | KDM4E (0.43) | PANK3ESR1ESR2PRMT5WDR77 | |
| SCHEMBL21267702 | 0.73 | KMT2A (0.45) | CHRNA7NR1H2NR1H3CNR2 | |
| SCHEMBL20994112 | 0.73 | ESR1 (0.39) | PANK3CHRNA7ESR1ESR2NR1H2 | |
| SCHEMBL24760211 | 0.72 | PANK3 (0.46) | PANK3ESR1ESR2PRMT5WDR77 | |
| Hydrochloric Acid SCHEMBL29268002 | 0.72 | GABRP (0.54) | PANK3ESR1ESR2SLC22A12CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | PANK3 96/4885CHRNA7 4724/4885ESR1 1847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.