Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25825557 | 0.75 | PANK3 (0.38) | CHRNA7PIK3CAMTORNR1H2ALOX5AP | |
| SCHEMBL2737265 | 0.74 | NOS3 (0.53) | CHRNA7ALDH1A1SMN1; SMN2NOS3NOS1 | |
| SCHEMBL17125687 | 0.74 | CYP19A1 (0.42) | KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL15627417 | 0.73 | GABRP (0.40) | CHRNA7ALDH1A1PROKR1GABRPGABRD | |
| SCHEMBL3507840 | 0.73 | LOXL2 (0.52) | CHRNA7NOS3NOS1NOS2 | |
| SCHEMBL12120626 | 0.73 | GABRA1 (0.40) | CHRNA7KDM4EPOLBSMN1; SMN2GABRA1 | |
| SCHEMBL5102672 | 0.73 | RECQL (0.52) | CHRNA7PROKR1GABRA1GABRG2GABRB3 | |
| SCHEMBL13069319 | 0.72 | NOS2 (0.37) | CHRNA7KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL23015825 | 0.71 | NR3C2 (0.40) | CHRNA7ALDH1A1GABRPGABRDGABRA1 | |
| SCHEMBL23006880 | 0.70 | GSR (0.42) | CHRNA7ALDH1A1NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | CHRNA7 4364/4885PIK3CA 3/4885MTOR 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.